Miss Noname is about a girl who grew up without a mother, or father, or name. When she was born, her mother had suffered a serious injury which took her life shortly before Noname's birth. Doctors wrote on her birth certificate "No name" as a placeholder until they could get a hold of a guardian, which was her grandmother. The registrars entered "No name" as her official name.
She lives by herself now due to her grandmother's recent passing away, jumping between her school life and her job at DreyBucks and trying to make ends meet at her apartment. That was until...